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Nature Medicine Logo

 

Artificial antigen-presenting cells as a tool to exploit the immune `synapse

 

Positive selection in autoimmunity: Abnormal immune responses to
a bacterial dnaJ antigenic determinant in patients with early rheumatoid arthritis

 


 

The Lancet logo

 

Tolerogenic immune responses to novel T-cell epitopes from heat-shock protein 60
in juvenile idiopathic arthritis

 



PNAS Logo

 

Epitope-specific immunotherapy induces immune deviation of proinflammatory
T cells in rheumatoid arthritis

 


 

Journal of Clinical Investigation Logo

 

Genetic bias in immune responses to a cassette
shared by different microorganisms in patients with rheumatoid arthritis.


Serum soluble interleukin 6 (IL-6) receptor and IL-6/soluble
IL-6 receptor complex in systemic juvenile rheumatoid arthritis.


The susceptibility sequence to rheumatoid arthritis is a cross-reactive B cell epitope
shared by the Escherichia coli heat shock protein dnaJ and the histocompatibility leukocyte antigen DRB10401 molecule.

 



Arthritis and Rheumatism Logo

 

Hsp60 in inflamed muscle tissue is the target of regulatory autoreactive T cells
in patients with juvenile dermatomyositis. Arthritis Rheum. 2008 Jan 31;58(2):547-555 [Epub ahead of print]


Differential recognition of heat-shock protein dnaJ-derived epitopes by effector
and Treg cells leads to modulation of inflammation in juvenile idiopathic arthritis


Exploiting T cell crosstalk as a vaccination strategy for rheumatoid arthritis


T cell epitope-specific immune therapy for rheumatic diseases


Antihistone antibodies in antinuclear antibody - positive juvenile Arthritis


Screening the genome for rheumatoid arthritis susceptibility genes:
A replication study and combined analysis of 512 multicase families


Inhibition of adjuvant-induced arthritis by interleukin-10-driven regulatory cells
induced via nasal administration of a peptide analog of an arthritis-related heat-shock protein 60 T cell epitope


Self epitopes shared between human skeletal myosin and Streptococcus pyogenes
M5 protein are targets of immune responses in active juvenile dermatomyositis


Proinflammatory responses to self HLA epitopes are triggered by molecular mimicry
to Epstein-Barr virus proteins in oligoarticular juvenile idiopathic arthritis

 


 

Annals of the Rheumatic Diseases Logo

 

Balancing the immune system: Th1 and Th2

 


arthritis research and therapy logo

 

Novel self-epitopes derived from aggrecan, fibrillin, and matrix metalloproteinase-3

drive distinct autoreactive T-cell responses in juvenile idiopathic arthritis and in health

 



international immunology logo

 

Novel pan-DR-binding T cell epitopes of adenovirus induce pro-inflammatory
cytokines and chemokines in healthy donors


 

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