Clinical Research Unit

The University of Arizona Arthritis Center (UAAC) is at the forefront of exciting advancements in arthritis and autoimmune diseases. Clinical trials have been conducted at the UAAC for more than 20 years. The Clinical Research Unit (CRU) offers a great opportunity for individuals who wish to participate in clinical research.

The Food and Drug Administration (FDA) requires that several different types of clinical trials be performed on new medications prior to approval. Subjects may benefit from research as well as contribute to the advancement of science.

Prior to its approval by the FDA, clinical trials for Remicade were conducted at the UAAC. Remicade is now available at the Biologic Infusion Center, located in our Rheumatology Clinic. For more information call 694-4000

HOW CAN YOU GET INVOLVED?

The Clinical Research Unit at the UAAC is currently recruiting people who have been diagnosed with rheumatoid arthritis, lupus, gout or scleroderma with digital ulcers to participate in clinical research studies. If you are interested in learning more about research studies involving these diseases, please contact the Clinical Research Unit and speak with a study coordinator.

CLINICAL TRIALS CURRENTLY OPEN FOR ENROLLMENT

A telephone call to a Clinical Research Coordinator can help to determine an individual's initial eligibility. The individual is then invited to the research clinic to learn specifically what the study will entail and what is expected of him or her. A physician explains the study and all questions will be answered prior to the informed consent document being signed. The individual has the option to withdraw their consent at anytime during the study, for any reason without impact on their current medical care.

Each study has different ratios of how many people receive the investigational drug versus a placebo. All subjects participating in a clinical trial will receive close medical monitoring by a rheumatologist. The clinical research subjects are seen at the University of Arizona Clinical and Translational Science Research Center.

SYSTEMIC LUPUS ERYTHEMATOSUS

Clinical Research Study

If you’re at least 18 years old and have lupus, you may qualify for a local research study of an investigational medication for managing lupus.
Qualified volunteers will receive at no cost:
•  Study medication
•  Study-related care from a local doctor
•  Reimbursement for your time and travel

Health insurance and referrals aren’t required to participate.

To learn more, please contact Susan at 520-626-8219 or smerski@email.arizona.edu.


GOUT STUDY

You may qualify to participate if you:

  • Female, 55 years or older
  • Male, 50 years or older
  • Have gout and a history of cardiac disease like stroke or heart attack or blood circulation problems

This is a nine-year study to evaluate the safety of Febuxostat and Allopurinol. Study-related medical care and services are provided at no cost to study participants. Compensation for time and travel will be provided.

If you are interested in more information or to see if you qualify, please contact Susan at 520-626-8219 or smerski@email.arizona.edu.

 

VASCULITIS CLINICAL RESEARCH STUDY

You may be able to participate in this study, if you:

  • are 18 years of age or older
  • have a diagnosis of Wegener’s granulomatosis (WG) or a diagnosis of microscopic polyangiitis (MPA)
  • have had an episode of moderately to severely active WG or MPA requiring treatment within the last 6 months

This study will evaluate the effectiveness and safety of belimumab in the maintenance of remission following a standard induction regimen in patients with WG or MPA. Study participation will last approximately 2 years or longer with monthly study visit. Study related medical care and services are provided at no cost to study participants.

If you are interested in more information or to see if you qualify, please contact Susan at 520-626-8219 or smerski@email.arizona.edu.

 

OSTEOARTHRITIS CLINICAL RESEARCH STUDY

 You may be able to participate in this study, if you:

  • are between the ages of 35 and 74, inclusive
  • have osteoarthritis of the knee
  • have active inflammation (including pain, joint stiffness, swelling) in the knee
  • are willing to discontinue your pain medication

This study will investigate the safety and effectiveness of the investigational study drug on osteoarthritis pain. Study participation will last approximately 13 months with study visits every 2 weeks. Study related medical care and procedures are provided at no cost to study participants.

If you are interested in more information or to see if you qualify, please contact Susan at 520-626-8219 or smerski@email.arizona.edu.

 

OSTEOARTHRITIS CLINICAL RESEARCH STUDY

You may be able to participate in this study if you:

  • are between the ages of 35 and 80 inclusive
  • have osteoarthritis of the hand
  • have one or more clinical signs and symptoms of active inflammation in at least three hand joints
  • are willing to discontinue your pain medication

This study will investigate the safety and effectiveness of the investigational study drug on osteoarthritis pain. Study participation will last approximately 7 months with study visits every 2 weeks. Study related medical care and procedures are provided at no cost to study participants.

If you are interested in more information or to see if you qualify, please contact Ali at 520-626-9235 or amcinnis@email.arizona.edu.

 

RHEUMATOID ARTHITIS CLINICAL RESEARCH STUDY

You may be able to participate in this study if you:

  • are 50 years of age or older
  • have been diagnosed with rheumatoid arthritis (RA) for at least 6 months
  • are currently taking methotrexate
  • still have RA symptoms despite having taken an RA medication
  • have one or more risk factors for heart disease, such as:
    • cigarette smoking
    • you or someone in your family has a history of a heart condition such as  heart attack, stroke, or heart disease
    • diabetes, high blood pressure, or high cholesterol
  • and are willing to comply with a schedule of medical visits and procedures.

This study will investigate the safety of tofacitinib when taken by people with rheumatoid arthritis. Study participation will last approximately 5 years with study visits monthly for three months and then every three months through Month 60. Study related medical care and procedures are provided at no cost to study participants.

If you are interested in more information or to see if you qualify, please contact Susan at 520-626-8219 or smerski@email.arizona.edu.

 

For information on clinical trials visit clinicaltrials.gov.